Silica Aerogel Improves the Biocompatibility in a Poly-ε-Caprolactone Composite Used as a Tissue Engineering Scaffold
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چکیده
منابع مشابه
Thermogel-Coated Poly(ε-Caprolactone) Composite Scaffold for Enhanced Cartilage Tissue Engineering
A three-dimensional (3D) composite scaffold was prepared for enhanced cartilage tissue engineering, which was composed of a poly(ε-caprolactone) (PCL) backbone network and a poly(lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(lactide-co-glycolide) (PLGA–PEG– PLGA) thermogel surface. The composite scaffold not only possessed adequate mechanical strength similar to native osteochond...
متن کاملLaser Sintered Magnesium-Calcium Silicate/Poly-ε-Caprolactone Scaffold for Bone Tissue Engineering
In this study, we manufacture and analyze bioactive magnesium-calcium silicate/poly-ε-caprolactone (Mg-CS/PCL) 3D scaffolds for bone tissue engineering. Mg-CS powder was incorporated into PCL, and we fabricated the 3D scaffolds using laser sintering technology. These scaffolds had high porosity and interconnected-design macropores and structures. As compared to pure PCL scaffolds without an Mg-...
متن کاملBiocompatibility of Poly-ε-caprolactone-hydroxyapatite composite on mouse bone marrow-derived osteoblasts and endothelial cells
BACKGROUND Tissue-engineered bone may be developed by seeding the cells capable of both osteogenesis and vascularization on biocompatible composite scaffolds. The current study investigated the performance of mice bone marrow-derived osteogenic cells and endothelial cells as seeded on hydroxyapatite (HA) and poly-epsilon-caprolactone (PCL) composite scaffolds. METHODS Mononuclear cells were i...
متن کاملbiocompatibility study of a hydroxyapatite-alumina and silicon carbide composite scaffold for bone tissue engineering
objective: to date, several scaffolds have been fabricated for application in bone tissue repair. however, there remains a need for synthesis of scaffolds with better mechanical properties, which can be applied to defects in weight-bearing bones. we constructed a composite ceramic bioscaffold of hydroxyapatite-alumina and silicon carbide (ha-al2o3- sic) to take advantage of the mechanical prope...
متن کاملMesoporous magnesium silicate-incorporated poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) bioactive composite beneficial to osteoblast behaviors
Mesoporous magnesium silicate (m-MS) and poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) (PCL-PEG-PCL) composite (m-MPC) was synthesized by solvent casting method. The results suggest that the mechanical properties of compressive strength and elastic modulus, as well as hydrophilicity, of the m-MPC increased with increase of m-MS content in the composites. In addition, the weigh...
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ژورنال
عنوان ژورنال: International Journal of Polymer Science
سال: 2013
ISSN: 1687-9422,1687-9430
DOI: 10.1155/2013/402859